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Divergent stereoselectivity in the reduction of α,β-Epoxy ketones using hydridosilicates

✍ Scribed by Makoto Hojo; Atsuko Fujii; Chikara Murakami; Hidenori Aihara; Akira Hosomi


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
228 KB
Volume
36
Category
Article
ISSN
0040-4039

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Highly stereoselective synthesis of eryt
✍ Tadashi Nakata; Tadasu Tanaka; Takeshi Oishi 📂 Article 📅 1981 🏛 Elsevier Science 🌐 French ⚖ 253 KB

Erythro-a, B-epoxy alcohols were prepared in high stereoselectivity by zinc borohydride reduction of the corresponding a, B-epoxy ketones regardless of the substituents on the epoxide ring. Epoxidation of the ally1 alcohols (L) with tert-butyl hydroperoxide catalyzed by VO(acac)2 was reported to giv