A flexible, efficient route to chiral 3-hydroxy-4-methyl-and 3-hydroxy-4-methoxyalkanoic acids, with high control of the C(3) configuration, has been disclosed, which is based on the borane-mediated reduction of ltrimethylsilyl-l-alkyn-3-ones (6) in the presence of oxazaborolidine 7 followed by hydr
✦ LIBER ✦
A synthetic approach towards octalactin A, based on the stereoselective reduction of α,β-unsaturated ketones
✍ Scribed by Jordi Bach; Ramon Berenguer; Jordi Garcia; Jaume Vilarrasa
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 245 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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