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Divergent role of the peripheral CrF1 and Crf2 receptor in the modulation of visceral pain in the freely moving rat

✍ Scribed by Marjoleen Nijsen; Nicolas Ongenae; Ann Meulemans; Bernard Coulie


Book ID
119427228
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
181 KB
Volume
124
Category
Article
ISSN
0016-5085

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Corticotropin-releasing factor (CRF), a 41 amino acid peptide exhibits its actions through two pharmacologically distinct CRF receptor subtypes CRF(1) and CRF(2). Regulation of the relative contribution of the two CRF receptors to central CRF activity may be essential in coordinating physiological r