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Divergent role for CRF1 and CRF2 receptors in the modulation of visceral pain

✍ Scribed by M. Nijsen; N. Ongenae; A. Meulemans; B. Coulie


Book ID
110850530
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
249 KB
Volume
17
Category
Article
ISSN
1350-1925

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Corticotropin-releasing factor (CRF), a 41 amino acid peptide exhibits its actions through two pharmacologically distinct CRF receptor subtypes CRF(1) and CRF(2). Regulation of the relative contribution of the two CRF receptors to central CRF activity may be essential in coordinating physiological r