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Divergent dysregulation of gene expression in murine models of fragile X syndrome and tuberous sclerosis

โœ Scribed by Kong, Sek; Sahin, Mustafa; Collins, Christin D; Wertz, Mary H; Campbell, Malcolm G; Leech, Jarrett D; Krueger, Dilja; Bear, Mark F; Kunkel, Louis M; Kohane, Isaac S


Book ID
125404290
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
330 KB
Volume
5
Category
Article
ISSN
2040-2392

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## Abstract Klinefelter's Syndrome (KS) is a chromosomal karyotype with one or more extra X chromosomes. KS individuals often show language impairment and the phenotype might be due to overexpression of genes on the extra X chromosome(s). We profiled mRNA derived from lymphoblastoid cell lines from