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Diuretic and antihypertensive effects of Sinorphan, an orally active inhibitor of atriopeptidase (EC 3.4.24.11)

✍ Scribed by C. Mossiat; J. Bralet; C. Gros; J.C. Schwartz; J.M. Lecomte


Book ID
115985295
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
100 KB
Volume
24
Category
Article
ISSN
0022-2828

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## Abstract Amiloride.HCl is clinically used as an oral potassium‐sparing diuretic, but multiple studies in biochemical, cellular and animal models have shown that the drug also possesses anti‐tumour and anti‐metastasis activities. The additional effects appear to arise through inhibition of two di