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Ditosylate Salt of Itraconazole and Dissolution Enhancement Using Cyclodextrins

✍ Scribed by Neeraj Kumar, Shishu, Gulshan Bansal, Sandeep Kumar, Asim Kumar Jana


Book ID
118729138
Publisher
Springer US
Year
2012
Tongue
English
Weight
725 KB
Volume
13
Category
Article
ISSN
1530-9932

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Phase-solubility techniques were used to assess the formation of inclusion complex between itraconazole and beta-cyclodextrin. The stability constant and free energies of transfer of itraconazole from aqueous solution to the cavity of beta-cyclodextrin were calculated. Itraconazole solubility in sup