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Disturbed B and T cell homeostasis and neogenesis in patients with ataxia telangiectasia

โœ Scribed by Kraus, Matan; Lev, Atar; Simon, Amos J.; Levran, Inbal; Nissenkorn, Andrea; Levi, Yonit B.; Berkun, Yackov; Efrati, Ori; Amariglio, Ninette; Rechavi, Gideon; Somech, Raz


Book ID
121791661
Publisher
Springer
Year
2014
Tongue
English
Weight
649 KB
Volume
34
Category
Article
ISSN
0271-9142

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Ataxia telangiectasia (A-T) is an autosomal recessive disorder in which patients show an unusual predisposition to malignant disease, including T-cell chronic lymphocytic leukaemia. We report here the steady growth over 5 years of a complex, cytogenetically abnormal clone of T lymphocytes in an A-T