DISTRIBUTION OF α1 -ANTITRYPSIN (PI) SUBTYPES FROM NEWBORNS
✍ Scribed by Mulley, John C
- Book ID
- 109864515
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1982
- Weight
- 185 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0004-945X
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📜 SIMILAR VOLUMES
Pi phenotypes have been determined by isoelectrofocusing in a sample of 538 healthy individuals from Southern Germany. Further subdivision of the common PiM phenotype is described. A procedure for the delineation of six common subtypes is presented. It is assumed that the six subtypes are determined
## Louis a,-antitrypsin (a1 AT) deficiency is variably associated with the development of pulmonary emphysema. To gain insight into the process which begins the Z point mutation at the Protease Inhibitor (Pi) locus and results in the variable development of emphysema, three quantitative phenotypes