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Classification ofα1-antitrypsin (Pi) phenotypes by isoelectrofocusing

✍ Scribed by Th. Genz; J. -P. Martin; H. Cleve

Publisher
Springer
Year
1977
Tongue
English
Weight
378 KB
Volume
38
Category
Article
ISSN
0340-6717

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✦ Synopsis

Pi phenotypes have been determined by isoelectrofocusing in a sample of 538 healthy individuals from Southern Germany. Further subdivision of the common PiM phenotype is described. A procedure for the delineation of six common subtypes is presented. It is assumed that the six subtypes are determined by three alleles which are provisionally called PiMa, PiMb, and PiMc. Their frequencies in this sample were 0.75, 0.06, and 0.15, respectively.

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