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Distribution of the enantiomers of hydroxychloroquine and its metabolites in ocular tissues of the rabbit after oral administration of racemic-hydroxychloroquine

โœ Scribed by Dr. Irving W. Wainer; John C. Chen; Heli Parenteau; Sami Abdullah; Julie Ducharme; Hiltrude Fieger; Joanna Iredale


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
853 KB
Volume
6
Category
Article
ISSN
0899-0042

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PHARMACOKINETICS OF THE ENANTIOMERS OF V
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Verapamil is a chiral calcium channel blocking drug which is useful clinically as the racemate in treating hypertension and arrhythmia. The published pharmacokinetic data for verapamil enantiomers in the rat model are limited. Utilizing a stereospeciยฎc highperformance liquid chromatographic (HPLC) a