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Distribution of plasminogen allotypes in eight populations of the Western Hemisphere

โœ Scribed by Dale Dykes; Mary Nelson; Herbert Polesky

Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
435 KB
Volume
4
Category
Article
ISSN
0173-0835

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โœฆ Synopsis

Abstract

Phenotyping for plasminogen (PLG) variants on 0.5 mm agarose isoelectric focusing gels enabled us to identify six different allotypes among the eight populations studied. PLG *1 and PLG *2 were seen at polymorphic frequencies in all the populations studied except Eskimos which had a gene frequency of 0.993 for PLG *1. The variants PLG *3, PLG *B, were seen at low frequencies in some of the populations, whereas PLG *M was only identified in the local White population. A new variant named PLG *D, which we consider to be a marker of black populations, was identified in local Blacks and Black Caribs at frequencies of 0.037 and 0.058, respectively.

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