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Distribution and Elimination of 2-MethyI-4-Chlorophenoxyacetic Acid (MCPA) in Male Rats

✍ Scribed by Elo, Heikki


Book ID
114799237
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
347 KB
Volume
39
Category
Article
ISSN
0001-6683

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Renal handling of 2-methyl-4-chloropheno
✍ Helmut BrΓ€unlich; Heike Bernhardt; Ingo Bernhardt πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 379 KB

Following i.p. administration of various doses of 2-methyl-4-chlorophenoxyacetic acid (MCPA), ca. 50% is excreted during a 5-h diuresis experiment. After i.p. administration of MCPA, virtually no distribution occurs (Vre, = 18% of the body weight). Renal excretion of MCPA can be accelerated by inhib