in breast carcinoma and other cancers
Distinctive patterns of Her-2/neu, c-myc, and cyclin D1 gene amplification by fluorescence in situ hybridization in primary human breast cancers
β Scribed by Laura E. Janocko; Kathryn A. Brown; Charles A. Smith; Ling Ping Gu; Agnese A. Pollice; Sarita G. Singh; Thomas Julian; Norman Wolmark; Lillian Sweeney; Jan F. Silverman; Stanley E. Shackney
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 558 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0196-4763
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π SIMILAR VOLUMES
Fluorescence in situ hybridization (FISH) is a validated method for detection of HER-2/neu gene amplification and was recently approved by the FDA for diagnostic use in paraffin-embedded tissue. Its use in cytologic specimens, however, has not been investigated. To see whether HER-2/neu gene amplifi
BACKGROUND. Amplification of the HER-2/neu oncogene has been proposed as a target for antibody-based therapies and as a predictor of chemoresponsiveness in advanced breast carcinoma. Few studies have concentrated on HER-2/neu gene evaluation by fluorescence in situ hybridization (FISH) on distant me
## Abstract ## BACKGROUND The objective of this article was to compare five tumor markers between white women in the U.S. and native Korean women with earlyβonset breast carcinoma. ## METHODS Sixty Korean women who were diagnosed with breast carcinoma at age 45 years or younger and 60 white wome