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Distinct roles for CD4 and CD8 as co-receptors in T cell receptor signalling

✍ Scribed by Christiane R. Maroun; Michael Julius

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
1015 KB
Volume
24
Category
Article
ISSN
0014-2980

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## T cell receptodCD3 and CD28 use distinct intracellular signaling pathways* Ligation of the T cell membrane antigen CD28 strongly enhances cytokine secretion in humanT lymphocytes that are activated viaTcell receptor (TcR)/CD3 or CD2 molecules.This study was undertaken to investigate whether, as