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Distinct pathways for the involvement of WNK4 in the signaling of hypertonicity and EGF

✍ Scribed by Miriam Shaharabany; Eliezer J. Holtzman; Haim Mayan; Koret Hirschberg; Rony Seger; Zvi Farfel


Book ID
111312339
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
526 KB
Volume
275
Category
Article
ISSN
1432-1327

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During vertebrate embryogenesis retinoic acid (RA) synthesis must be spatiotemporally regulated in order to appropriately stimulate various retinoid signaling pathways. Various forms of mammalian aldehyde dehydrogenase (ALDH) have been shown to oxidize the vitamin A precursor retinal to RA in vitro.