Distinct Expression of Galectin-3 in Pheochromocytomas
β Scribed by OLIVER GIMM; ULF KRAUSE; MICHAEL BRAUCKHOFF; CUONG HOANG-VU; HENNING DRALLE
- Book ID
- 111479551
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 271 KB
- Volume
- 1073
- Category
- Article
- ISSN
- 0890-6564
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Galectin-1 and galectin-3 are galactoside-binding proteins involved in different steps of tumor progression and potential targets for therapy. We have investigated the expression of these galectins in 38 human bladder transitional-cell carcinomas of different histological grade and clinical stage an
## Abstract Galectinβ3 is an endogenous mammalian carbohydrateβbinding protein with affinity for ABH group carbohydrate epitopes and polylactosamine glycans present on cell surface and extracellular matrix glycoproteins. It has been shown to play a role in cell differentiation, morphogenesis, adhes