Dissymmetric chromophores. II. Circular dichroism of (2R)-bicycl[3·1·0]hexan-2-one and(2S)-6,6-dimethylbicyclo[3·1·0]hexane-2-one.
✍ Scribed by David A. Lightner; Dennis E. Jackman
- Publisher
- Elsevier Science
- Year
- 1975
- Tongue
- French
- Weight
- 237 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Lettera-No, 35, pp 3051 -3054, 1975. Per-Pm=i. printed in Great Bdt~in* DISSYWETRIC CHRCMOPHORES. 1I.l CIRCULAR DICHROISM OF (2E)-BICYCL0[3.1-OIHEXAN-2-ONE AND (2S)-6,6-DIMETHYLBICYCLO[3~1~O]HEXANE-2-ONE.
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Synthesis of the chiral bicyclic ketone mentioned in the title starting from Rcarvone, and its elaboration to 7-epibakkenolide-A is described. Conjugate addition of dimethyl copperlithium to R-carvone followed by alkylation of the intermediate enolate generated the allylated compound 6, which was tr
In continuing our investigations of the reactivity of highly strained molecules "\* we started a study of the behaviour of ',2,5,6-tetramethyl-3,4-dimethylenetricyclo[3.'.0.0 2,6 lhexane '3 in cycloaddition reactions. Of special interest is the interaction of the bicyclobutane and diene moiety in th