Dissolution kinetics of a three-component solid I: Ehtylparaben, phenacetin, and salicylamide

✍ Scribed by Michael Simpson; Eugene L. Parrott

• Publisher: John Wiley and Sons
• Year: 1983
• Tongue: English
• Weight: 685 KB
• Volume: 72
• Category: Article
• ISSN: 0022-3549
• DOI: 10.1002/jps.2600720711

✦ Synopsis

The dissolution rates of each component in compressed spheres consisting of three components were measured under sink conditions. A film diffusion model is discussed and presented diagrammatically to illustrate the 13 possible dissolution behaviors of a three-component solid. Experimental dissolution rates compare favorably to dissolution rates calculated according to the model a t mass fractions representative of the 13 dissolution behaviors Keyphrases 0 Ethylparabendissolution kinetics of a three-component solid, phenacetin, salicylamide Phenacetin-dissolution kinetics of a three-component solid, ethylparaben, salicylamide 0 Salicylamidedissolution kinetics of a three-component solid, ethylparaben, phenacetin ' Patterson-Kelly. Carver press, model C.