## Abstract It is known that dibutyryl cyclic AMP (dbcAMP) and theophylline inhibit the spontaneous maturation of isolated mouse oocytes. The present study demonstrates that dbcAMP (0.01 – 1.0 mM) as well as cyclic AMP (cAMP, 10 mM) and a phosphodiesterase inhibitor (IBMX, 0.01 – 1.0 mM) prevent sp
Dissociation of Preovulatory Maturational Events in Rat Oocytes and Cumuli in the Presence of Dibutyryl Cyclic AMP
✍ Scribed by Hillensjö, Torbjörn
- Book ID
- 114867060
- Publisher
- John Wiley and Sons
- Year
- 1977
- Tongue
- English
- Weight
- 227 KB
- Volume
- 100
- Category
- Article
- ISSN
- 0001-6772
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## Abstract Mouse oocytes arrested in dictyate of the first meiotic prophase by dibutyryl cyclic AMP accumulated exogenous valine at the same rate as oocytes undergoing meiotic maturation. The apparent rate of protein synthesis and the spectrum of proteins synthesized were not significantly affecte
## Abstract Cytogenetic data are presented which indicate species differences in the response of oocytes maturing in vitro in the presence of dibutyryl cyclic AMP (dbcAMP). Inhibition of ewe oocyte maturation was noted at germinal vesicle, MI, and MII in the presence of 25–750 μg/ml of dbcAMP. Cow