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Dissociation Constants of Substituted Aryl Azo Barbituric and Thiobarbituric Acids

✍ Scribed by Masoud, M.S.; Ghonaim, A.K.; Ahmed, R.H.; Mahmoud, A.A.; Ali, A.


Book ID
120077658
Publisher
Oldenbourg Wissenschaftsverlag
Year
2001
Tongue
German
Weight
82 KB
Volume
215
Category
Article
ISSN
0942-9352

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## Abstract A sodium derivative of 1,3‐dimefhylbarbituric acid or 1,3‐diethyl‐2‐thiobarbituric acid undergoes an efficient monoacylation at C5 by the reaction with ω‐chloroalkanoyl chloride or diacid dichloride in the presence of pyridine in tetrahydrofuran. A nucleophilic displacement of the chlor