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Dissecting the Nucleosomal Barrier to Transcription

✍ Scribed by Ishibashi, Toyotaka; Bintu, Lacramioara; Dangkulwanich, Manchuta; Gloria, Wu; Lubkowska, Lucyna; Kashlev, Mikhail; Bustamante, Carlos


Book ID
122234739
Publisher
Biophysical Society
Year
2012
Tongue
English
Weight
64 KB
Volume
102
Category
Article
ISSN
0006-3495

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Nucleosome positioning is proposed to have an essential role in facilitating the regulated transcription of eukaryotic genes. Some transcription factors can bind to DNA when it is appropriately wrapped around the histone core, others cannot hind due to the severe deformation of DNA structure. The st