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Dissecting the Chemistry of Protein Splicing and Its Applications

โœ Scribed by Christopher J. Noren; Jimin Wang; Francine B. Perler

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
332 KB
Volume
39
Category
Article
ISSN
0044-8249

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Protein splicing is an extraordinary post-translational reaction that removes an intact central "spacer" domain (Sp) from precursor proteins (N-Sp-C) while splicing together the N-and C-domains of the precursor, via a peptide bond, to produce a new protein (N-C). All of the available data on protein