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Disruption of tumor necrosis factor-α gene prevents the development of atherosclerosis in apoE-deficient mice

✍ Scribed by H Fujii; H Wada; K Saito; N Maekawa; S Fujigaki; H Kirii; K Sekikawa; M Seishima

Book ID
119434345
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
144 KB
Volume
151
Category
Article
ISSN
0021-9150

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✍ Narci Teoh; Jacqueline Field; Jaim Sutton; Geoffrey Farrell 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 356 KB

Although hepatic ischemia-reperfusion (IR) injury is partially mediated by tumor necrosis factor-alpha (TNF), we recently found that low-dose TNF before IR is hepatoprotective. We examined the seemingly conflicting roles of TNF in mediating liver injury in a partial hepatic IR model using TNF gene k