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Disruption of transforming growth factor β-Smad signaling pathway in head and neck squamous cell carcinoma as evidenced by mutations of SMAD2 and SMAD4

✍ Scribed by Wanglong Qiu; Frank Schönleben; Xiaojun Li; Gloria H. Su

Book ID: 116334129
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 196 KB
Volume: 245
Category: Article
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2006.01.003

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## Abstract The objective of this study was to determine whether transforming growth factor alpha (TGF alpha) levels could be used as nonspecific tumor markers in patients with advanced squamous cell carcinoma (SCC) of the head and neck. Fourteen patients with epidermoid carcinoma of the head and n