## Background: Head and neck squamous cell carcinomas (hnsccs) were previously shown to express a repertoire of cytokines and angiogenesis factors that contribute to malignant pathogenesis and are detectable in serum. pretreatment and posttreatment serum levels of cytokines and angiogenesis factors
Investigation of urinary transforming growth factor alpha levels as tumor markers in patients with advanced squamous cell carcinoma of the head and neck
โ Scribed by Mary Fazekas-May; Dr. James Y. Suen; Yun Chi Yeh; Hsing Wu Yeh; Lynda Beth Milligan
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 436 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1043-3074
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โฆ Synopsis
Abstract
The objective of this study was to determine whether transforming growth factor alpha (TGF alpha) levels could be used as nonspecific tumor markers in patients with advanced squamous cell carcinoma (SCC) of the head and neck. Fourteen patients with epidermoid carcinoma of the head and neck were followed with serial urine TGF alpha levels, and the results were compared with the extent of cancer and the course of the disease. Based on the findings of this study further research is necessary before urine TGF levels can be recommended as a routine screening test for SCC of the head and neck.
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