𝔖 Bobbio Scriptorium
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Disruption of the first extracellular loop of thyrotropin receptor prevents ligand binding

✍ Scribed by K. Haraguchi; T. Saito; T. Endo; T. Onaya

Book ID
118346711
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
500 KB
Volume
55
Category
Article
ISSN
0024-3205

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## Abstract The cannabinoid receptor one (CB1) is a class A G‐protein‐coupled receptor thought to bind ligands primarily within its helical bundle. Evidence suggests, however, that the extracellular domain may also play a role. We have previously shown that the C‐terminus of the extracellular loop