Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs
β Scribed by Rogers, C. S.; Stoltz, D. A.; Meyerholz, D. K.; Ostedgaard, L. S.; Rokhlina, T.; Taft, P. J.; Rogan, M. P.; Pezzulo, A. A.; Karp, P. H.; Itani, O. A.
- Book ID
- 115470323
- Publisher
- American Association for the Advancement of Science
- Year
- 2008
- Tongue
- English
- Weight
- 978 KB
- Volume
- 321
- Category
- Article
- ISSN
- 0036-8075
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
German patients with cystic fibrosis (CF) were screened for molecular lesions in exon 13 of the cystic fibrosis transmembrane conductance regulator (CFTR) gene by single strand conformation polymorphism (SSCP) and chemical cleavage of mismatch analyses. Direct sequencing of four samples that display
Cystic fibrosis is a common, fatal disorder caused by abnormalities in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. CFTR encodes a chloride channel that regulates secretion in many exocrine tissues. The presentation of cystic fibrosis is highly variable as measured by the age