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Spectrum of Mutations in the CFTR Gene in Cystic Fibrosis Patients of Spanish Ancestry

✍ Scribed by M. J. Alonso; D. Heine-Suñer; M. Calvo; J. Rosell; J. Giménez; M. D. Ramos; J. J. Telleria; A. Palacio; X. Estivill; T. Casals


Book ID
111111315
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
85 KB
Volume
71
Category
Article
ISSN
0003-4800

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The cystic fibrosis transmembrane conductance regulator (CFTR) gene of 110 cystic fibrosis (CF) patients from the south-west of Germany was screened for 12 different mutations. This analysis resulted in an identification of 79% of all CF mutations and a complete genotype in 66% of the families. The