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Disruption of HPV 16 E1 and E2 genes in precancerous cervical lesions

✍ Scribed by Monica Cricca; Simona Venturoli; Elisa Leo; Silvano Costa; Monica Musiani; Marialuisa Zerbini


Book ID
113768005
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
144 KB
Volume
158
Category
Article
ISSN
0166-0934

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## Abstract The presence of the E2 region of HPV 16 was determined by the polymerase chain reaction in biopsy samples with different histopathological diagnoses. The absence of the E2 gene was observed in 17 of 30 cases examined. The E2 deletions were not confined exclusively to invasive carcinomas