We microdissected 15 specimens of invasive cervical cancer co-existing with some of its precursors. Out of 15 cases, 10 carried HPV16, 2 HPV31, 1 HPV18 and 2 were HPVnegative. We found 3 HPV16 E6 variants among the 10 cases; one was A = = G in nt 131 (one case) and a second was A = = G in nt 276. Th
The E2 region of HPV 16 in relation to different types of cervical lesions
β Scribed by Dr. Maja Krajinovic; Jelena Lazic; Branko Stanimirovic; Vukosava Diklic; Ana Savic
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 500 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0146-6615
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
The presence of the E2 region of HPV 16 was determined by the polymerase chain reaction in biopsy samples with different histopathological diagnoses. The absence of the E2 gene was observed in 17 of 30 cases examined. The E2 deletions were not confined exclusively to invasive carcinomas or to integrated viral forms. In the majority of cases, the course of cervical lesions was consistent with the state of the E2 gene.
π SIMILAR VOLUMES
## Abstract Highβrisk human papillomaviruses (HPVs) are risk factors for the development of cervical cancer. HPV 16 is the most common type, being present in about 60% of cervical cancers worldwide. Previous studies have reported upon the association between HPV 16 E6 variants and increased risk of
## Abstract Human papillomavirus (HPV) types causing anogenital lesions and cancer are accepted as being sexually transmitted. The methods whereby children acquire these anogenital type HPV infections are unclear. The present study determined the prevalence of antiβHPVβ16, HPVβ11 and HPVβ18 IgG ant