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Disposition of pyrethroids in the rat central nervous system

✍ Scribed by Maria Rosa Martínez-Larrañaga; Marta Martínez; Maria Aranzazu Martínez; Victor Castellano; Virginia Caballero; Arturo Anadón


Book ID
119380350
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
75 KB
Volume
180
Category
Article
ISSN
0378-4274

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We studied the effect of pyridostigmine bromide, a nerve agent prophylactic, on the central nervous system (CNS) uptake of [ 14 C]permethrin, a pyrethroid insecticide, at scaled human-equivalent exposures in rats using accelerator mass spectrometry (AMS). AMS detects 14 C at attomole sensitivities a