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Disposition of procainamide in subjects with low or high CYP2D6 activity.

✍ Scribed by Lessaxd, E.; Bélanger, P.M.; Hamelin, B. A.; Turgeon, J.

Book ID
111717687
Publisher
Nature Publishing Group
Year
1996
Tongue
English
Weight
165 KB
Volume
59
Category
Article
ISSN
0009-9236

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## Abstract P450 enzymes are of high interest for synthetic applications due to their ability to catalyze hydroxylation reactions at inactivated C–H bonds. The low solubility of many substrates in buffer, however, is limiting the applications of P450s. Our recent demonstration that the P450 enzymes