Disposition of ibuprofen in nephrectomized dogs
โ Scribed by D. S.-L. Au; T. H. Kuo; C. S. Lee; B. Mederski-Samoraj
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 441 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Ibuprofen is a nonsteroidal antiinflammatory agent extensively used in the treatment of pain and inflammatory disorders (1). Most pharmacokinetic studies of ibuprofen have involved healthy young male volunteers (2-6). However, patients who use ibuprofen for clinical purposes are often elderly and ma
The percutaneous absorption and disposition of iodochlorhydroxyquin (5-chloro-7-iodo-8-quinolinol; I) from a 3% cream were studied in five dogs over a 28-d topical treatment period. Plasma levels, determined by HPLC, were 0.275-0.525 microgram/mL. The steady-state elimination rate of total I in urin