Disposition of high-dose methotrexate in an obese cancer patient
β Scribed by Ronald A. Fleming; Russell M. Eldridge; Christopher E. Johnson; Clinton F. Stewart
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 316 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0008-543X
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π SIMILAR VOLUMES
## BACKGROUND. Administration of recombinant high dose interleukin-2 (IL-2) can mediate tumor regression in patients with metastatic melanoma and renal carcinoma. Significant trends in the safety of high dose IL-2 administration at a single institution over a 12-year study period were reviewed. #
## Abstract ## Objective To examine the longβterm efficacy of lowβdose intravenous methotrexate (MTX) with and without concomitant glucocorticoids (GC) for remission maintenance in patients with generalized Wegener's granulomatosis (WG) in an openβlabel, prospective, standardized trial. ## Method