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Disposition of allylic oxidation pathway metabolites of racemic hexobarbital in the rat

✍ Scribed by M. Van Der Graaff; N. P. E. Vermeulen; M. H. A. M. Vinks; D. D. Breimer


Book ID
113006559
Publisher
Springer-Verlag
Year
1986
Tongue
English
Weight
606 KB
Volume
11
Category
Article
ISSN
0378-7966

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## Abstract The main objective of this study was to determine the pharmacokinetics of the enantiomers of desbutylhalofantrine (DHF), a metabolite of halofantrine (HF), in the rat. Rats received either intravenous (2 mg/kg) or oral (7 mg/kg) (Β±)‐DHF HCl, or (Β±)‐HF HCl intravenously (3 mg/kg). Enanti