Disposition, Explanation, and Causation—A Defense of the Reformed Conditional Analysis of Disposition
✍ Scribed by Jaeho Lee
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 126 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0048-3893
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📜 SIMILAR VOLUMES
An approach based on disposition decomposition analysis (DDA) and the hysteresis minimization principle has been developed for pharmacodynamic modeling. It allows calculation of the mean transit time and the ratio of distribution clearance to biophase distribution volume of drug, and determination o
The disposition of inulin was studied in 30 healthy male and 10 healthy female volunteers, and 10 patients with stable chronic renal failure (mean creatinine clearance 45 ml.min-1) following intravenous infusion of 70 mg.kg-1 over 5 min. Plasma concentrations fell rapidly initially but the rate of d