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Dispersed type expression of p53 tumor suppressor gene protein is associated with a poor prognosis in patients with oral cancer

✍ Scribed by A. Yamaguchi; H. Hiratsuka; H. Dehari; K. Tomihara; K. Ogi

Book ID: 116560672
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 135 KB
Volume: 36
Category: Article
ISSN: 0901-5027
DOI: 10.1016/j.ijom.2007.09.003

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## Abstract HDAC genes are thought to be involved in gene expression through the regulation of chromatin structure, alterations of which may cause abnormal gene silencing in cancers. To clarify the possible role of HDAC genes during tumor development and progression, we studied their expression and