P-glycoprotein (Pgp) encoded by the MDR1 gene, a predictor of chemoresistance, may also serve as a prognosticator of clinical outcome in cancer patients. The mutant tumour-suppressor p53 protein has been shown to activate the MDR1 promoter, whereas the wild-type p53 represses this activity in cultur
Coexpression of Ets-1 and p53 in oral carcinomas is associated with P-glycoprotein expression and poor prognosis
โ Scribed by S. Soni; P. Pande; N. Shukla; R. Ralhan
- Publisher
- Springer-Verlag
- Year
- 2002
- Tongue
- English
- Weight
- 172 KB
- Volume
- 128
- Category
- Article
- ISSN
- 1432-1335
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