We have used a human salivary gland cell line (HSG) as a possible in vitro model to evaluate the effects of IFN-g on human salivary gland epithelium (Wu et al., , 1996(Wu et al., , 1997)). In the present study, we examined the JAK-STAT signal-transduction pathway in IFN-g-treated HSG cells. We demon
Dispensability of Jak1 tyrosine kinase for interleukin-2-induced cell growth signaling in a human T cell line
β Scribed by Masaya Higuchi; Hironobu Asao; Nobuyuki Tanaka; Katsuhiko Oda; Toshikazu Takeshita; Masataka Nakamura; Jacques Van Snick; Kazuo Sugamura
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 752 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0014-2980
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## Abstract HKH40A (RTA 502), or 5βnitroβ2β(3β{4β[3β(8βmethoxyβ6βoxoβ6Hβ2,10bβdiazaβaceanthrylenβ5βylamino)propyl]piperazinβ1βyl}βpropyl)β2βazaβphenaleneβ1,3βdione, has been shown to be a potent cell growth inhibitor. To investigate HKH40A actions, we focused on exploring the signal transduction pa