Disorders of pyruvate carboxylase and the pyruvate dehydrogenase complex
β Scribed by B. H. Robinson; N. MacKay; K. Chun; M. Ling
- Publisher
- Springer
- Year
- 1996
- Tongue
- English
- Weight
- 873 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0141-8955
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The pyruvate dehydrogenase complex has been demonstrated in high speed pellet preparations from sonicated ribbed mussel gill mitochondria. The activity of the complex is inhibited by low chloride (< 100 mM) concentrations, EDTA (1 mM), succinate, ATP, and NAD/NADH ratios below 4. Inhibition by EDTA