After initial exposure to 80 mg/kg, pigeons trained on a two-key drug discrimination procedure rapidly learned to discriminate 120 mg/kg ethosuximide from saline. When 40-160 mg/kg doses of ethosuximide were administered during generalization tests, the percentage of responses directed to the ethosu
Discriminative stimulus properties of valproic acid in the pigeon
โ Scribed by Mitchell Picker; Scott Wallace; Susan Hancock; Alan Poling
- Publisher
- Springer
- Year
- 1985
- Tongue
- English
- Weight
- 600 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0033-3158
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๐ SIMILAR VOLUMES
Pigeons trained under a two-key drug discrimination procedure eventually learned to discriminate 5 mg/kg phenytoin from saline injections. When 1.25-20 mg/kg doses of phenytoin were substituted for the training dose, the percentage of responses directed to the phenytoin-appropriate key varied direct
Pigeons were trained to discriminate an IM injection of racemic pentobarbital sodium (5.0 mg/kg) from saline under a second-order color-tracking schedule of mixed grain presentation. In a time-course study, maximal pentobarbital-appropriate responding occurred 15 min after administration of 5.0 mg/k
The ability of CNS stimulants to block the discriminative effects ofpentobarbital was studied in pigeons trained to discriminate IM pentobarbital (5 mg/kg) from saline. Pentobarbital, when administered alone, consistently produced greater than 90}' 0 pentobarbital-appropriate responding. The concomi