✦ LIBER ✦

Discrimination of isomers by liquid ionization mass spectrometry with techniques of collisional activation and adduct ion formation

✍ Scribed by Yoshiko Niki; Masahiko Tsuchiya

Publisher: John Wiley and Sons
Year: 1987
Tongue: English
Weight: 516 KB
Volume: 22
Category: Article
ISSN: 1076-5174
DOI: 10.1002/oms.1210220308

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✦ Synopsis

Liquid ionization mass spectrometry is a soft ionization technique used with liquid samples under atmospheric pressure. It facilitates the handling of reagents and the observation of ion-molecule reactions in the ion source. The differentiation of isomers by characteristic fragment ions, for example those resulting from asymmetrical cleavage of a cyclobutane ring, and by molecular adduct ion formation was studied. The samples studied were cyclobutane derivatives, alkyl 4-(3-0~0-3-phenyl-l-alkenyl)benzoate dimers, and reagents having two functional groups were used to produce adduct ions to clarify the difference between isomers. The reagents act on a sample molecule at two functional groups to form hydrogen bonds. Some correlations were observed between the structure of the sample and the relative abundances of molecular adduct ions and also fragment ions produced by collisionally activated dissociation.

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