✦ LIBER ✦

Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295

✍ Scribed by Qian, Xiangping; McDonald, Andrew; Zhou, Han-Jie; Adams, Nicholas D.; Parrish, Cynthia A.; Duffy, Kevin J.; Fitch, Duke M.; Tedesco, Rosanna; Ashcraft, Luke W.; Yao, Bing; Jiang, Hong; Huang, Jennifer K.; Marin, Melchor V.; Aroyan, Carrie E.; Wang, Jianchao; Ahmed, Seyed; Burgess, Joelle L.; Chaudhari, Amita M.; Donatelli, Carla A.; Darcy, Michael G.; Ridgers, Lance H.; Newlander, Ken A.; Schmidt, Stanley J.; Chai, Deping; Colón, Mariela; Zimmerman, Michael N.; Lad, Latesh; Sakowicz, Roman; Schauer, Stephen; Belmont, Lisa; Baliga, Ramesh; Pierce, Daniel W.; Finer, Jeffrey T.; Wang, Zhengping; Morgan, Bradley P.; Morgans, David J.; Auger, Kurt R.; Sung, Chiu-Mei; Carson, Jeff D.; Luo, Lusong; Hugger, Erin D.; Copeland, Robert A.; Sutton, David; Elliott, John D.; Jackson, Jeffrey R.; Wood, Kenneth W.; Dhanak, Dashyant; Bergnes, Gustave; Knight, Steven D.

Book ID: 127243857
Publisher: American Chemical Society
Year: 2010
Tongue: English
Weight: 937 KB
Volume: 1
Category: Article
ISSN: 1948-5875
DOI: 10.1021/ml900018m

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

First-time-in-human study of GSK923295,

First-time-in-human study of GSK923295, a novel antimitotic inhibitor of centromere-associated protein E (CENP-E), in patients with refractory cancer

✍ Vincent Chung; Elisabeth I. Heath; William R. Schelman; Brendan M. Johnson; Lynd 📂 Article 📅 2011 🏛 Springer 🌐 English ⚖ 397 KB

Discovery and Development of an Efficien

Discovery and Development of an Efficient, Scalable, and Robust Route to the Novel CENP-E Inhibitor GSK923295A

✍ Bellingham, Richard; Buswell, A. Mark; Choudary, Bernie M.; Gordon, Andrew H.; M 📂 Article 📅 2010 🏛 American Chemical Society 🌐 English ⚖ 547 KB

Discovery of the first potent and select

Discovery of the first potent and selective Mycobacterium tuberculosis Zmp1 inhibitor

✍ Mori, Mattia; Moraca, Francesca; Deodato, Davide; Ferraris, Davide M.; Selchow, 📂 Article 📅 2014 🏛 Elsevier Science 🌐 English ⚖ 507 KB

The Discovery of Setileuton, a Potent an

The Discovery of Setileuton, a Potent and Selective 5-Lipoxygenase Inhibitor

✍ Ducharme, Yves; Blouin, Marc; Brideau, Christine; Châteauneuf, Anne; Gareau, Yv 📂 Article 📅 2010 🏛 American Chemical Society 🌐 English ⚖ 966 KB

Discovery of a Potent and Selective Prot

Discovery of a Potent and Selective Protein Kinase CK2 Inhibitor by High-Throughput Docking

✍ Vangrevelinghe, Eric; Zimmermann, Kaspar; Schoepfer, Joseph; Portmann, Robert; F 📂 Article 📅 2003 🏛 American Chemical Society 🌐 English ⚖ 214 KB

The Discovery of I-BET726 (GSK1324726A),

The Discovery of I-BET726 (GSK1324726A), a Potent Tetrahydroquinoline ApoA1 Up-Regulator and Selective BET Bromodomain Inhibitor

✍ Gosmini, Romain; Nguyen, Van Loc; Toum, Jérôme; Simon, Christophe; Brusq, Jean-M 📂 Article 📅 2014 🏛 American Chemical Society 🌐 English ⚖ 963 KB