Discovery of novel 2-[2-(3-hydroxy-pyridin-2-yl)-thiazol-4-yl]-acetamide derivatives as HIF prolyl 4-hydroxylase inhibitors; SAR, synthesis and modeling evaluation
✍ Scribed by Hong, Yong Rae; Kim, Hyun Tae; Ro, Seonggu; Cho, Joong Myung; Lee, Sang Hwi; Kim, In Su; Jung, Young Hoon
- Book ID
- 122276606
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 761 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0960-894X
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## Abstract magnified image A series of novel bis‐[3‐(2‐arylmethylidenimino‐1,3‐thiazol‐4‐yl)‐4‐hydroxy‐__2H__‐chromen‐2‐one‐6‐yl]methane **7a**, **7b**, **7c**, **7d**, **7e**, **7f** and bis‐[3‐(2‐arylidenhydrazo‐1,3‐thiazol‐4‐yl)‐4‐hydroxy‐__2H__‐chromen‐2‐one‐6‐yl]‐methane **8a**, **8b**, **8c
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