Discovery of N -(3-Fluorophenyl)-1-[(4-([(3 S )-3-methyl-1-piperazinyl]methyl)phenyl)acetyl]-4-piperidinamine (GSK962040), the First Small Molecule Motilin Receptor Agonist Clinical Candidate

✍ Scribed by Westaway, Susan M.; Brown, Samantha L.; Fell, Stephen C. M.; Johnson, Christopher N.; MacPherson, David T.; Mitchell, Darren J.; Myatt, James W.; Stanway, Steven J.; Seal, Jon T.; Stemp, Geoffrey; Thompson, Mervyn; Lawless, Kirk; McKay, Fiona; Muir, Alison I.; Barford, Jonathan M.; Cluff, Chermaine; Mahmood, Sadhia R.; Matthews, Kim L.; Mohamed, Shiyam; Smith, Beverley; Stevens, Alexander J.; Bolton, Victoria J.; Jarvie, Emma M.; Sanger, Gareth J.

• Book ID: 127284036
• Publisher: American Chemical Society
• Year: 2009
• Tongue: English
• Weight: 179 KB
• Volume: 52
• Category: Article
• ISSN: 0022-2623
• DOI: 10.1021/jm801332q