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Discovery of Low-Molecular-Weight Ligands for the AF6 PDZ Domain

✍ Scribed by Mangesh Joshi; Carolyn Vargas; Prisca Boisguerin; Annette Diehl; Gerd Krause; Peter Schmieder; Karin Moelling; Volker Hagen; Markus Schade; Hartmut Oschkinat

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
517 KB
Volume
118
Category
Article
ISSN
0044-8249

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This study tests the feasibility of inhalable pegylated liposomal formulations of low molecular weight heparin (LMWH) for treatment of two clinical manifestations of vascular thromboembolism: deep vein thrombosis (DVT) and pulmonary embolism (PE). Conventional distearoyl-sn-glycero-3-phosphoethanola