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Discovery of hydroxamic acid analogs as dual inhibitors of phosphodiesterase-1 and -5

✍ Scribed by Akihito Dan; Takaaki Shiyama; Kazuto Yamazaki; Naoto Kusunose; Katsuya Fujita; Hideshi Sato; Kazutaka Matsui; Masafumi Kitano


Book ID
108073708
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
611 KB
Volume
15
Category
Article
ISSN
0960-894X

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πŸ“œ SIMILAR VOLUMES


Mesoionic xanthine analogs as inhibitors
✍ R. A. Glennon; M. E. Rogers; R. G. Bass; S. B. Ryan πŸ“‚ Article πŸ“… 1978 πŸ› John Wiley and Sons 🌐 English βš– 383 KB

Several derivatives of two mesoionic xanthine analogs, mesoionic thiazolo[3,2-alpha]pyrimidine-5,7-diones and mesoionic 1,3,4-thiadiazolo[3,2-alpha]pyrimidine-5,7-diones, were synthesized and evaluated as inhibitors of cyclic AMP phosphodiesterase. A significant number of these compounds demonstrate