Discordant encephalocele in monozygotic twins
โ Scribed by V. de P. Djientcheu; A. Wonkam; A.K. Njamnshi; P. Ongolo-Zogo; B. Rilliet; M.A. Morris
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 71 KB
- Volume
- 140A
- Category
- Article
- ISSN
- 1552-4825
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We report on monozygotic (MZ) twins, one with the fibular aplasia developmental field defect, and the other with ectrosyndactyly of the hand. This may represent a coincidental occurrence of two sporadic events, or syndro-ma1 fibular aplasia.
## Abstract Monochorionic twins were phenotypically discordant for Down syndrome. Chromosome analysis of lymphocytes showed both to be mosaics. Fibroblast chromosome analysis showed that one twin was 46,XY and the other 47,XY, +21. Blood mosaicism appears to have resulted from placental anastomoses