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Discordance of T-cell receptor β-chain genes in familial multiple sclerosis

✍ Scribed by Sharon G. Lynch; Dr. John W. Rose; Jack H. Petajan; Dora Stauffer; Craig Kamerath; Mark Leppert


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
728 KB
Volume
30
Category
Article
ISSN
0364-5134

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To better characterize the inflammatory response that occurs in the nervous system in multiple sclerosis (MS), T-cell receptor (TCR) gene expression was quantified from cerebrospinal fluid (CSF) cells of 21 patients with active disease. Unstimulated CSF cells expressed each of 22 different TCR beta